We present information from 75 nests of Gray-crowned Tyrannulet (Serpophaga griseiceps) found in open Prosopis woodlands of the central Monte desert between 1995 and 1997 and compare it with information corresponding to other species of the genus. Breeding occurred from October to January. Nests are small open cups. Both parents participated in nest building, which lasted 4–7 days. In the Prosopis woodland, 98% of the nests were built in chañar (Geoffroea decorticans), which also is commonly used as a nest plant by S. subcristata in east-central Argentina. Mean clutch size did not vary among years nor within the breeding season, and it was similar to that observed in other Serpophaga. Both male and female shared the 13–15 day incubation period. Hatching was asynchronous. Nestling period lasted 13–14 days, during which both parents reared the chicks. Nesting success (26%) appeared to be less than that previously reported for Nearctic open-nesters (50–60%), and Neotropical open-nesters in dry (50%) and wet tropics (35%). Egg and nestling predation were the main cause of nest failure.